Abstract: 2D-3D registration is central to image guided minimal invasive endovascular therapies such as the treatment of aneurysms. We propose a novel intensity-based 2D-3D registration method based on digitally reconstructed radiographs and the so-called Normalized Gradient Fields (NGF) as a distance measure. We evaluate our method on publicly available clinical data and compare it to five other state-of-the-art 2D-3D registration methods. The results show that our method achieves better accuracy with comparable results in terms of the number of successful registrations and robustness.
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