Abstract: Highlights•The first quantification for the 3D distance and volume of brain mid-surface shift.•A novel end-to-end 3D CNN architecture integrating multiple tasks and domains.•An efficient plane detection scheme based on the differentiable deep Hough transform.•Considering the hematoma factor boosts segmentation and quantification performance.•Extensive validation and state-of-the-art performance on internal and public datasets.
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