Feasibility of waveform separation of central aortic pressure pulse based on lognormal flow wave approximation

Liling Hao, Qi Zhang, Xuewei Chen, Yudong Yao, Lisheng Xu

Abstract: Highlights•A novel method for waveform separation of central aortic pressure using a single pressure pulse measurement together with a lognormal flow wave approximation.•Calculate the wave reflection parameters including reflection amplitude (RM) and reflection index (RI), and the aortic pulse transit time (PTT) based on the separated forward and backward waves.•The lognormal flow wave, a more physiological waveform, for approximating the flow able to improve the results of wave separation analysis in both time and frequency domains.