CF-Loss: Clinically-relevant feature optimised loss function for retinal multi-class vessel segmentation and vascular feature measurement

Yukun Zhou, Moucheng Xu, Yipeng Hu, Stefano B. Blumberg, An Zhao, Siegfried K. Wagner, Pearse A. Keane, Daniel C. Alexander

Abstract: Highlights•Encoding clinically-relevant vascular features as an end-to-end loss function.•Proposed CF-Loss improves multi-class vessel segmentation and vascular feature measurement.•Highlight importance of optimising vascular feature in model training.•Investigate CF-Loss contribution to ischaemic stroke prediction.