Homotopic local-global parcellation of the human cerebral cortex from resting-state functional connectivity

Xiaoxuan Yan, Ru Kong, Aihuiping Xue, Qing Yang, Csaba Orban, Lijun An, Avram J. Holmes, Xing Qian, Jianzhong Chen, Xi-Nian Zuo, Juan Helen Zhou, Marielle V. Fortier, Ai Peng Tan, Peter D. Gluckman, Yap-Seng Chong, Michael J. Meaney, Danilo Bzdok, Simon B. Eickhoff, B. T. Thomas Yeo

Abstract: Highlights•We extended the Schaefer parcellations to a new set of homotopic, areal-level parcellations.•The resulting homotopic parcellations are as homogeneous as the Schaefer parcellations and more homogeneous than 5 publicly available parcellations, across 4 datasets.•The homotopic parcellations agree with the boundaries of cortical areas estimated from histology and visuotopic fMRI.•Homotopic correlation patterns are associated with lateralization in resting network organization, as well as lateralization in language and motor task activation.