[CS582Reading Assignment 1-2] Sequence modeling and design from molecular to genome scale with Evo

Ge Liu

Keywords: Hyena, long-context genome LM

Abstract:

**Additional Question 1**

Do you think the scaling law in genomic studies will be the same as in natural language studies? What could make the scaling law different/similar for genomic studies compared to natural language?

**Additional Question 2**

How would you interpret the result in section 2.4.3. Predicting gene expression from regulatory DNA, and what are the implications of the better performance of the Evo model?

Submission Number: 2