Deep learning based segmentation of brain tissue from diffusion MRI

Fan Zhang, Anna Breger, Kang Ik Kevin Cho, Lipeng Ning, Carl-Fredrik Westin, Lauren J. O'Donnell, Ofer Pasternak

Abstract: Highlights•A novel deep learning method for WM, GM and CSF segmentation directly using dMRI data.•A novel augmented target loss function that penalizes segmentation errors at tissue boundaries.•A good generalizability to dMRI data from a clinical acquisition with a lower resolution and fewer gradient directions.