Toward Automatic Tumor-Stroma Ratio Assessment for Survival Analysis in Colorectal CancerDownload PDF

20 Apr 2022, 12:21 (edited 04 Jun 2022)MIDL 2022 Short PapersReaders: Everyone
  • Keywords: Computational pathology, tumor-stroma ratio, colorectal cancer
  • TL;DR: We present a fully automated system for TSR scoring in line with current recommendations for pathologists, based on tumor and tumor-adjacent stroma tissue detection.
  • Abstract: In this paper, we present a fully automated system for tumor-stroma ratio scoring in line with current recommendations for pathologists, based on tumor and tumor-adjacent stroma tissue detection. In order to evaluate the scoring system, we perform survival analysis on 221 whole slide images from colorectal cancer patients. We find that the whole slide-level and region of interest-level tumor-stroma ratio are statistically significant predictors of overall survival.
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  • Paper Type: recently published or submitted journal contributions
  • Primary Subject Area: Application: Histopathology
  • Secondary Subject Area: Detection and Diagnosis
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