Ontology-guided machine learning outperforms zero-shot foundation models for cardiac ultrasound text reports

Published: 14 Feb 2025, Last Modified: 20 Dec 2025Scientific ReportsEveryoneRevisionsCC BY 4.0
Abstract: Big data can revolutionize research and quality improvement for cardiac ultrasound. Text reports are a critical part of such analyses. Cardiac ultrasound reports include structured and free text and vary across institutions, hampering attempts to mine text for useful insights. Natural language processing (NLP) can help and includes both statistical- and large language model based techniques. We tested whether we could use NLP to map cardiac ultrasound text to a three-level hierarchical ontology. We used statistical machine learning (EchoMap) and zero-shot inference using GPT. We tested eight datasets from 24 different institutions and compared both methods against clinician-scored ground truth. Despite all adhering to clinical guidelines, institutions differed in their structured reporting. EchoMap performed best with validation accuracy of 98% for the first ontology level, 93% for first and second levels, and 79% for all three. EchoMap retained performance across external test datasets and could extrapolate to examples not included in training. EchoMap’s accuracy was comparable to zero-shot GPT at the first level of the ontology and outperformed GPT at second and third levels. We show that statistical machine learning can map text to structured ontology and may be especially useful for small, specialized text datasets. Authors: [All authors listed here, as I couldn't find all authors profile on open review] Suganya Subramaniam, Sara Rizvi, Ramya Ramesh, Vibhor Sehgal, Brinda Gurusamy, Hikmatullah Arif, Jeffrey Tran, Ritu Thamman, Emeka C Anyanwu, Ronald Mastouri, G. Burkhard Mackensen & Rima Arnaout Link to paper: https://www.nature.com/articles/s41598-024-83540-y#citeas Keywords: Natural language processing, Machine learning, Large language models, Echocardiography report, Ontology
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