Relax and focus on brain tumor segmentation

Pei Wang, Albert C. S. Chung

Abstract: Highlights•Severe data imbalance for tumor and non-tumor tissues, and among tumor sub-regions.•Loss function is dynamically updated for each class based on its performance.•Focus on harder classes with smaller sizes, complex structures, rough boundaries.•Recognize the structural relationships of tumor sub-regions.•Balance the learning capacity for global features and spatial details.