Semantic consistency-guided patch-wise relation graph reasoning scheme for lung cancer organoid segmentation in brightfield microscopy

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Tianxu Lv, Jiansong Fan, Zexin Chen, Yuan Liu, Jianming Ni, Wei Chu, Xiang Pan

Published: 01 Jan 2025, Last Modified: 12 Nov 2025Comput. Methods Programs Biomed. 2025EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: Highlights•Semantic-guided patch-wise graph reasoning for live PDO segmentation.•PRGCM integrates texture info for global semantic dependency.•Multi-task learning for enhanced edge and semantic details.•Our method outperforms state-of-the-art approaches.