Ambiguity-aware breast tumor cellularity estimation via self-ensemble label distribution learning

Xiangyu Li, Xinjie Liang, Gongning Luo, Wei Wang, Kuanquan Wang, Shuo Li

Abstract: Highlights•A novel ambiguity modeling method for effective inter-rater ambiguity exploitation.•A new label distribution generation method tailored for the TC estimation task.•A novel restricted distribution loss with unimodal and mean value regularization.•The first work leverages inter-rater and intra-rater ambiguity for TC estimation.