Drug repositioning based on tripartite cross-network embedding and graph convolutional network

Pan Zeng, Bofei Zhang, Aohang Liu, Yajie Meng, Xianfang Tang, Jialiang Yang, Junlin Xu

Abstract: Highlights•The study has identified novel candidate drugs for osteosarcoma.•The proposed method facilitates node embedding and information integration.•Cross-network embedding improves drug-disease association prediction performance.