Acquisition-invariant brain MRI segmentation with informative uncertainties

Pedro Borges, Richard Shaw, Thomas Varsavsky, Kerstin Kläser, David Thomas, Ivana Drobnjak, Sébastien Ourselin, M. Jorge Cardoso

Abstract: Highlights•Algorithmic generalisability and harmonisation can feature in a single model.•Sequence-aware, physics-aware augmentations allows for this to be done.•Uncertainty can be leveraged to validate and increase the safety of these predictions.•Uncertainty and physics of acquisition modelling could assist in sequence optimisation.