Spectral Analysis of Mitochondrial Dynamics: A Graph-Theoretic Approach to Understanding Subcellular Pathology

Marcus Hill, Mojtaba Sedigh Fazli, Rachel Mattson, Meekail Zain, Andrew Durden, Allyson T. Loy, Barbara Reaves, Abigail Courtney, Frederick D. Quinn, S. Chakra Chennubhotla, Shannon P. Quinn

Abstract: Perturbations of organellar structures within a cell are useful indicators of the cell’s response to viral or bacterial invaders. Of the various organelles, mitochondria are meaningful to model because they show distinct migration patterns in the presence of potentially fatal infections, such as tuberculosis.