Prior-knowledge-embedded model predictive control for blood glucose regulation: Towards efficient and safe artificial pancreas

Open Webpage

Xiaoyu Sun, Ali Cinar, Jianchang Liu, Mudassir M. Rashid, Xia Yu

Published: 2023, Last Modified: 05 Oct 2025Biomed. Signal Process. Control. 2023EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: Highlights•Presented a prior-knowledge-embedded glucose prediction model based on latent variables.•Presented MPC based on prior-knowledge-embedded latent variable model.•Proposed constraint based on blood glucose concentration prevents hypoglycemia.•Developed a novel safe fully-automated artificial pancreas system based on MPC.