Abstract: Highlights•A novel federated fusion learning (FFL) framework for multi-client data fusion.•FFL as a solution for statistical heterogeneity and label scarcity in clients’ data.•A multi-client latent space fusion module for various modality latent space fusion.•Detailed investigation of 19 diverse medical image datasets for generalization.•Excellent generalizability and promising performance of the global model via FFL.
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