Multi-view progression diagnosis of thyroid cancer by integrating platelet transcriptomes and blood routine tests

Yi Lai, Dong Xu, Kewei Li, Lin Song, Yiming Chen, He Li, Zhaoyang Hu, Fengfeng Zhou, Jiaqing Zhou, Yuling Shen

Abstract: Highlights•A multiview framework ThyroidBloodTest performed best on thyroid cancer diagnosis.•A prediction model of four-class thyroid cancer progression was presented.•PEPPER engineers well the features of both transcriptomes and blood routine data.•The multiview features may be further enriched by PCA.•A large cohort of 152 RNAseq samples was recruited and released to public.