Deep Local Analysis evaluates protein docking conformations with locally oriented cubes

Yasser Mohseni Behbahani, Simon Crouzet, Elodie Laine, Alessandra Carbone

Abstract: With the recent advances in protein 3D structure prediction, protein interactions are becoming more central than ever before. Here, we address the problem of determining how proteins interact with one another. More specifically, we investigate the possibility of discriminating near-native protein complex conformations from incorrect ones by exploiting local environments around interfacial residues.