Improved identification of tumors in 18F-FDG-PET examination by normalizing the standard uptake in the liver based on blood test data

Md. Ashraful Alam, Shouhei Hanaoka, Yukihiro Nomura, Tomohiro Kikuchi, Takahiro Nakao, Tomomi Takenaga, Naoto Hayashi, Takeharu Yoshikawa, Osamu Abe

Abstract: Standardized uptake values (SUVs) derived from 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography are a crucial parameter for identifying tumors or abnormalities in an organ. Moreover, exploring ways to improve the identification of tumors or abnormalities using a statistical measurement tool is important in clinical research. Therefore, we developed a fully automatic method to create a personally normalized Z-score map of the liver SUV.