50 shades of overfitting: towards MRI-based neurologicalmodels interpretationDownload PDF

Mar 26, 2021 (edited Apr 20, 2021)MIDL 2021 Conference Short SubmissionReaders: Everyone
  • Keywords: 3DCNN, MRI, saliency maps, GradCAM, augmentation, gradcam
  • TL;DR: Applying saliency methods for 3DCNN interpretation to avoid overfitting of gender prediction models on healthy subjects.
  • Abstract: MRI-based prediction models are one of the most exploited AI solutions in neurology. Numerous computer-vision models showed their predictive ability for diverse psychoneurological conditions. Although most of these models are based on weak or no annotation, only a few reported studies interpret the predictions and perform the model saliency regions' analysis. We utilize 3DCNN interpretation with GradCAM to explore learned patterns for basic demographic characteristics prediction on the healthy cohort. We compare the saliency maps of the gender prediction models with the different types of MRI data preprocessing and augmentation. We assess the quality of learned patterns and examine the ways of models overfitting. We propose a data augmentation strategy based on optimal transport to avoid model overfitting on the brain volumes.
  • Paper Type: methodological development
  • Primary Subject Area: Interpretability and Explainable AI
  • Secondary Subject Area: Detection and Diagnosis
  • Paper Status: original work, not submitted yet
  • Source Code Url: https://github.com/PolinaDruzhinina/CrystalNeuroimaging
  • Data Set Url: https://www.humanconnectome.org/study/hcp-young-adult
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  • Authorship: I confirm that I am the author of this work and that it has not been submitted to another publication before.
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