A hierarchical attention network integrating multi-scale relationship for drug response prediction

Xiaoqi Wang, Yuqi Wen, Yixin Zhang, Chong Dai, Yaning Yang, Xiaochen Bo, Song He, Shaoliang Peng

Abstract: Highlights•Hierarchical attention network for drug response prediction.•Integrating the internal and external relationship in biomedical entities.•Achieving higher performance than baselines on various prediction scenarios.•Great ability distinguishing sensitive and resistant drugs for cancer cell lines.