Überatlas: Fast and robust registration for multi-atlas segmentation

Jennifer Alvén, Alexander Norlén, Olof Enqvist, Fredrik Kahl

Abstract: Highlights•The registration step in multi-atlas segmentation is efficiently and robustly solved.•An intermediate atlas representation for feature-based registration is constructed.•Clustering establishes feature clusters describing distinctive anatomical landmarks.•Running times are significantly reduced compared to standard registration methods.•Segmentation results are comparable to state-of-the-art for cardiac CT and brain MRI.