A physical activity-intensity driven glycemic model for type 1 diabetes

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Nicole Hobbs, Sediqeh Samadi, Mudassir M. Rashid, Andrew Shahidehpour, Mohammad-Reza Askari, Min-Sun Park, Laurie Quinn, Ali Cinar

Published: 2022, Last Modified: 05 Oct 2025Comput. Methods Programs Biomed. 2022EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: Highlights•Factors that affect the glycemic response include the intensity and duration of physical activity, plasma insulin concentrations, and the individual physical fitness level.•To model the glycemic response for a person with type 1 diabetes to physical activity, these factors must be considered.•Several physiological models describing the glycemic response to physical activity are proposed by incorporating various model terms.•A model with terms accommodating endogenous glucose production, glucose transfer, and insulin-independent glucose utilization enable an improved estimation of glycemic responses to physical activity.