A cognitive state transformation model for task-general and task-specific subsystems of the brain connectome

Kwangsun Yoo, Monica D. Rosenberg, Young Hye Kwon, Dustin Scheinost, R. Todd Constable, Marvin M. Chun

Abstract: Highlights•We present a novel connectome-to-connectome (C2C) transformation modeling framework.•The C2C models can predict individual task-specific connectomes from task-free connectome.•The C2C-transformed task connectomes outperform task-free data to predict behavior.•This approach quantitatively models how the brain reconfigures across mental states.