Effect of guidewire insertion in fractional flow reserve procedure for real geometry using computational fluid dynamics

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Yasser Abuouf, Muhamed AlBadawi, Shinichi Ookawara, Mahmoud Ahmed

Published: 01 Dec 2021, Last Modified: 27 Nov 2025BioMedical Engineering OnLineEveryoneRevisionsCC BY-SA 4.0
Abstract: Coronary artery disease is an abnormal contraction of the heart supply blood vessel. It limits the oxygenated blood flow to the heart. Thus, diagnosing its severity helps physicians to select the appropriate treatment plan. Fractional flow reserve (FFR) is the most accurate method to pinpoint the stenosis severity. However, inserting the guidewire across stenosis may cause a false overestimation of severity.