Model-based super-resolution reconstruction for pseudo-continuous Arterial Spin Labeling

Quinten Beirinckx, Piet Bladt, Merlijn C. E. van der Plas, Matthias J. P. van Osch, Ben Jeurissen, Arnold J. den Dekker, Jan Sijbers

Abstract: Highlights•High-resolution quantitative CBF mapping from 2D multi-slice single-PLD pCASL data.•Joint estimation of perfusion and motion parameters.•Bayesian estimation to exploit prior knowledge of the tissue and noise statistics.•Improved background suppression compared to conventional 2D multi-slice readout.•Validation using whole brain Monte Carlo simulations and in vivo brain data.