PathFL: Multi-alignment Federated Learning for pathology image segmentation

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Yuan Zhang, Feng Chen, Yaolei Qi, Guanyu Yang, Huazhu Fu

Published: 01 Jan 2025, Last Modified: 12 Nov 2025Medical Image Anal. 2025EveryoneRevisionsBibTeXCC BY-SA 4.0
Abstract: Highlights•PathFL is a multi-alignment federated framework for pathology image segmentation.•Image-level collaborative style enhancement shares client styles to boost diversity.•Feature-level adaptive feature alignment ensures consistent representation learning.•Aggregation-level stratified similarity aggregation improves global generalization.•PathFL achieves superior and robust performance across domains, organs, and scanners.