Sparse balance: Excitatory-inhibitory networks with small bias currents and broadly distributed synaptic weights

Ramin Khajeh, Francesco Fumarola, L. F. Abbott

Abstract: Author summary A class of models in computational neuroscience that have been successful at describing a variety of effects in the neocortex involve a tight balance between excitatory, inhibitory and unrealistically large external input, without which the model cannot produce robust patterns of activity. In this work, we explore what happens when these inputs are smaller in size, and we provide an alternative solution for recovering robust network activity. This solution relies on broadly distributed synaptic strengths and, interestingly, gives rise to sparse subsets of neurons firing at any given time. Unlike the conventional models, the networks exhibit nonlinear responses to uniform external input.