Cell Interrupted — Modeling Epithelial to Mesenchymal Transition vs. Mitochondrial Dysfunction-Associated Senescence Tug of War

NetSciX 2026 Conference Submission106 Authors

Keywords: Boolean model, cellular regulatory networks, EMT, senescence, cell cycle

TL;DR: This work offers a predictive mechanistic Boolean regulatory network model that explains the mutually exclusive nature of two cell fates seen in damaged tissues: transition to a migratory state and senescence in damaged cells.

Submission Number: 106