Design of a Configurable 16-Electrode Sense and Stimulation Neuromodulation System

Nathan Lopresto, Phuong Cao, Lucas J. Koerner, Heather Orser

Abstract: Electrical sensing and stimulation of nervous system activity is a valuable tool to investigate neural activity both in vivo and in vitro. A general system capable of supporting users across a variety of use cases would be valuable for the field of neuroscience. We propose a new system capable of supporting a variety of experimental cases including low and high impedance electrodes with stimulation amplitudes up to multiple mA. The system is designed to support sampling frequencies up to 26 kHz and to maximize stimulation flexibility with an electrically isolated system.