Multimodal Prescriptive Deep Learning

TMLR Paper4084 Authors

29 Jan 2025 (modified: 21 Apr 2025)Rejected by TMLREveryoneRevisionsBibTeXCC BY 4.0
Abstract: We introduce a multimodal deep learning framework, Prescriptive Neural Networks (PNNs), that combines ideas from optimization and machine learning, and is, to the best of our knowledge, the first prescriptive method to handle multimodal data. The PNN is a feedforward neural network trained on embeddings to output an outcome-optimizing prescription. In two real-world multimodal datasets, we demonstrate that PNNs prescribe treatments that are able to significantly improve estimated outcomes in transcatheter aortic valve replacement (TAVR) procedures by reducing estimated postoperative complication rates by 32% and in liver trauma injuries by reducing estimated mortality rates by over 40%. In four real-world, unimodal tabular datasets, we demonstrate that PNNs outperform or perform comparably to other well-known, state-of-the-art prescriptive models; importantly, on tabular datasets, we also recover interpretability through knowledge distillation, fitting interpretable Optimal Classification Tree models onto the PNN prescriptions as classification targets, which is critical for many real-world applications. Finally, we demonstrate that our multimodal PNN models achieve stability across randomized data splits comparable to other prescriptive methods and produce realistic prescriptions across the different datasets.
Submission Length: Long submission (more than 12 pages of main content)
Previous TMLR Submission Url: https://openreview.net/forum?id=YoBKP2Fiau
Changes Since Last Submission: Fixed margins per previous desk rejection. Made appropriate changes per reviewers' feedback. Made remaining changes per reviewers' feedback.
Assigned Action Editor: ~Devendra_Singh_Dhami1
Submission Number: 4084
Loading

OpenReview is a long-term project to advance science through improved peer review with legal nonprofit status. We gratefully acknowledge the support of the OpenReview Sponsors. © 2025 OpenReview