NotifAI-OS: an AI framework for automated CT-based opportunistic screening in post-acute value-based care

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Rohit Reddy, Perry J. Pickhardt, Arjun Manrai, Ronald M. Summers, David Kim, Pranav Rajpurkar

Published: 31 Oct 2025, Last Modified: 17 Mar 2026Nature Biomedical EngineeringEveryoneRevisionsCC BY-SA 4.0
Abstract: NotifAI-OS (notification artificial intelligence for opportunistic screening) is a conceptual deep learning-based framework that performs automated multi-target analysis of computed tomography examinations through quantitative tissue density and volumetric measurements to enable comprehensive disease screening during routine computed tomography examinations.