MMedAgent-RL: Optimizing Multi-Agent Collaboration for Multimodal Medical Reasoning

Peng Xia, Jinglu Wang, Yibo Peng, Kaide Zeng, Zihan Dong, Xian Wu, Xiangru Tang, Hongtu Zhu, Yun Li, Linjun Zhang, Shujie LIU, Yan Lu, Huaxiu Yao

Keywords: med-vlm, multi-agent collaboration, multimodal medical reasoning, medical vqa, reinforcement learning

Abstract: Medical Large Vision-Language Models (Med-LVLMs) have shown strong potential in multimodal diagnostic tasks. However, existing single-agent models struggle to generalize across diverse medical specialties, limiting their performance. Recent efforts introduce multi-agent collaboration frameworks inspired by clinical workflows, where general practitioners (GPs) and specialists interact in a fixed sequence. Despite improvements, these static pipelines lack flexibility and adaptability in reasoning. To address this, we propose MMedAgent-RL, a reinforcement learning (RL)-based multi-agent framework that enables dynamic, optimized collaboration among medical agents. Specifically, we train two GP agents based on Qwen2.5-VL via RL: the triage doctor learns to assign patients to appropriate specialties, while the attending physician integrates the judgments from multi-specialists and its own knowledge to make final decisions. To address the inconsistency in specialist outputs, we introduce a curriculum learning (CL)-guided RL strategy with dynamic entropy regulation, progressively teaching the attending physician to balance between imitating specialists and correcting their mistakes. Experiments on five medical VQA benchmarks demonstrate that MMedAgent-RL outperforms both open-source and proprietary Med-LVLMs. Notably, it achieves an average performance gain of 23.6\% over strong baselines.

Primary Area: applications to physical sciences (physics, chemistry, biology, etc.)

Submission Number: 7891