Towards personalized healthcare without harm via bias modulation

Published: 06 Mar 2025, Last Modified: 01 May 2025SCSL @ ICLR 2025EveryoneRevisionsBibTeXCC BY 4.0
Track: tiny / short paper (up to 3 pages)
Keywords: Personalized Machine Learning, Bias Modulation, Group Performance Optimization
TL;DR: Novel architecture for personalization without harm in machine learning
Abstract: Clinical prediction models are often personalized to target heterogeneous sub-groups by using demographic attributes such as race and gender to train the model. Traditional personalization approaches involve using demographic attributes in input features or training multiple sub-models for different population subgroups (decoupling model). However, these methods often harm the performance at the subgroup level compared to non-personalized models. This paper presents a novel personalization method to improve model performance at the sub-group level. Our method involves a two-step process: first, we train a model to predict group attributes, and then we use this model to learn data-dependent biases to modulate a second model for diagnosis prediction. Our results demonstrate that this joint architecture achieves consistent performance gains across all sub-groups in the Heart dataset. Furthermore, in the mortality dataset, it improves performance in two of the four sub-groups. A comparison of our method with the traditional decoupled personalization method demonstrated a greater performance gain in the sub-groups with less harm. This approach offers a more effective and scalable solution for personalized models, which could have a positive impact in healthcare and other areas that require predictive models that take sub-group information into account.
Anonymization: This submission has been anonymized for double-blind review via the removal of identifying information such as names, affiliations, and identifying URLs.
Submission Number: 51
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