TG-DGM: Clustering Brain Activity using a Temporal Graph Deep Generative ModelDownload PDF

Apr 06, 2021 (edited May 31, 2021)MIDL 2021 Conference Short SubmissionReaders: Everyone
  • Keywords: Temporal Graph, Generative Model, Deep Learning, Functional Magnetic Resonance Imaging
  • Abstract: Spatiotemporal graphs are a natural representation of dynamic brain activity derived from functional magnetic imaging (fMRI) data. Previous works, however, tend to ignore time dynamics of the brain and focus on static graphs. In this paper, we propose a temporal graph deep generative model (TG-DGM) which clusters brain regions into communities that evolve over time. In particular, subject embeddings capture inter-subject variability and its impact on communities using neural networks. We validate our model on the UK Biobank data. Results of up to 0.81 AUC ROC on the task of biological sex classification demonstrate that injecting time dynamics in our model outperforms a static baseline.
  • Paper Type: both
  • Primary Subject Area: Unsupervised Learning and Representation Learning
  • Secondary Subject Area: Application: Other
  • Paper Status: original work, not submitted yet
  • Source Code Url: We are working on a full journal publication and would rather submit the code then.
  • Data Set Url: We are working on a full journal publication and would prefer to open source the data then.
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