Evaluating the efficacy of multi-echo ICA denoising on model-based fMRI

Adam Steel, Brenda D. Garcia, Edward Harry Silson, Caroline E. Robertson

Abstract: Highlights•Multi-echo fMRI with TE-dependent denoising (ME-ICA) increases TSNR and improves pRF model fitting compared to single echo EPI.•ME-ICA improves the reliability of pRF parameter estimation.•Overall, ME-ICA may require as little as 1/3 data of single echo fMRI to achieve comparable pRF modeling performance.