Neural Stochastic Differential Equations on Compact State Spaces: Theory, Methods, and Application to Suicide Risk Modeling

Malinda Lu, Yue-Jane Liu, Matthew K. Nock, Yaniv Yacoby

Keywords: Stochastic Differential Equations, Compact Spaces, Latent SDEs, Mental Health, Suicide Prevention, Time Series, Viability Theory, Ecological Momentary Assessment

TL;DR: We develop a method to transform arbitrary neural/expert-given SDE dynamics to provably remain within clinically meaningful bounds (described by compact polyhedra), showing improved forecasts on real suicide-risk data over standard latent SDEs.

Abstract: Ecological Momentary Assessment (EMA) studies enable the collection of high-frequency self-reports of suicidal thoughts and behaviors (STBs) via smartphones. Latent stochastic differential equations (SDEs) are a promising model class for EMA data, as it is irregularly sampled, noisy, and partially observed. But SDE-based models suffer from two key limitations. (a) These models often violate domain constraints, undermining scientific validity and clinical trust of the model. (b) Training is numerically unstable without ad hoc fixes (e.g. oversimplified dynamics) that are ill-suited for high-stakes applications. Here, we develop a novel class of expressive SDEs whose solutions are provably confined to a prescribed compact polyhedral state space, matching the domains of EMA data. In this work, (1) we show why chain-rule based constructions of SDEs on compact domains fail, theoretically and empirically; (2) we derive constraints on drift and diffusion for general and stationary SDEs so their solutions remain in the desired state space; and (3), we introduce a parameterization that maps arbitrary (neural or expert-given) dynamics into constraint-satisfying SDEs. On several real EMA datasets, including a large suicide-risk study, our parameterization improves forecasts and optimization dynamics over standard latent neural SDE baselines. These contributions pave the way for principled, trustworthy continuous-time models of suicide risk and other clinical time series and extend applications of SDE-based methods (e.g. diffusion models) to domains with hard state constraints.

Submission Number: 12