ECG-MoE: Mixture-of-Expert Electrocardiogram Foundation Model

Yuhao Xu, Xiaoda Wang, Yi Wu, Wei Jin, Xiao Hu, Carl Yang

Keywords: Medical, Electrocardiogram, Foundation Model, Time Series, Period

Abstract: Electrocardiography (ECG) analysis is crucial for cardiac diagnosis, yet existing foundation models often fail to capture the periodicity and diverse features required for varied clinical tasks. We propose ECG-MoE, a hybrid architecture that integrates multi-model temporal features with a cardiac period-aware expert module. Our approach uses a dual-path Mixture-of-Experts to separately model beat-level morphology and rhythm, combined with a hierarchical fusion network using LoRA for efficient inference. Evaluated on five public clinical tasks, ECG-MoE achieves state-of-the-art performance with 40% faster inference than multi-task baselines.

Submission Number: 72