Optimizing Resources for On-the-Fly Label Estimation with Multiple Unknown Medical Experts

Published: 19 Aug 2025, Last Modified: 12 Oct 2025BHI 2025EveryoneRevisionsBibTeXCC BY 4.0
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Keywords: Ground Truth Inference, Computer-in-the-Loop Diagnosis, Decision Making in Medicine, AI for Medical Diagnosis.
TL;DR: This paper proposes a ground truth inference algorithm that is fit for integration into medical screening programs.
Abstract: Accurate ground truth estimation in medical screening programs often relies on coalitions of experts and peer second opinions. Algorithms that efficiently aggregate noisy annotations can enhance screening workflows, particularly when data arrive continuously and expert proficiency is initially unknown. However, existing algorithms do not meet the requirements for seamless integration into screening pipelines. We therefore propose an adaptive approach for real-time annotation that (I) supports on-the-fly labeling of incoming data, (II) operates without prior knowledge of medical experts or pre-labeled data, and (III) dynamically queries additional experts based on the latent difficulty of each instance. The method incrementally gathers expert opinions until a confidence threshold is met, providing accurate labels with reduced annotation overhead. We evaluate our approach on three multi-annotator classification datasets across different modalities. Results show that our adaptive querying strategy reduces the number of expert queries by up to 50% while achieving accuracy comparable to a non-adaptive baseline.
Track: 4. Clinical Informatics
Registration Id: QPNMKYBQ8R7
Submission Number: 250
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