Local Gamma Augmentation for Ischemic Stroke Lesion Segmentation on MRI

Jon Middleton, Marko Bauer, Kaining Sheng, Jacob Johansen, Mathias Perslev, Silvia Ingala, Mads Nielsen, Akshay Pai

Keywords: segmentation, classification, data augmentation, deep learning

TL;DR: This paper features a technique on locally augmenting pathological regions in human brain MRIs for improving the sensitivity and specificity of a U-Net.

Abstract: The identification and localisation of pathological tissues in medical images continues to command much attention among deep learning practitioners. When trained on abundant datasets, deep neural networks can match or exceed human performance. However, the scarcity of annotated data complicates the training of these models. Data augmentation techniques can compensate for a lack of training samples. However, many commonly used augmentation methods can fail to provide meaningful samples during model fitting. We present local gamma augmentation, a technique for introducing new instances of intensities in pathological tissues. We leverage local gamma augmentation to compensate for a bias in intensities corresponding to ischemic stroke lesions in human brain MRIs. On three datasets, we show how local gamma augmentation can improve the image-level sensitivity of a deep neural network tasked with ischemic lesion segmentation on magnetic resonance images.

Submission Number: 59