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OmegAMP: Targeted AMP Discovery via Biologically Informed Generation
Diogo Soares, Leon Hetzel, Paulina Szymczak, Marcelo Der Torossian Torres, Johanna Sommer, Cesar de la Fuente-Nunez, Fabian J Theis, Stephan Günnemann, Ewa Szczurek
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
Reading TEA leaves for de novo protein design
Lorenzo Pantolini, Janani Durairaj
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
DeepPrime7: Predicting PE7 Prime Editing Efficiency Across PAM Variants
Yumin Cheong, Yunyoung Choi, Hui Kwon Kim, Hyongbum Henry Kim
- Published: 02 Mar 2026, Last Modified: 10 Apr 2026
- GEM 2026
- Readers: Everyone
Sample Efficient Generative Molecular Optimization with Joint Self-Improvement
Serra Korkmaz, Adam Izdebski, Jonathan Pirnay, Rasmus Møller-Larsen, Michal Kmicikiewicz, Pankhil Gawade, Dominik G. Grimm, Ewa Szczurek
- Published: 02 Mar 2026, Last Modified: 15 Apr 2026
- GEM 2026
- Readers: Everyone
Structural plausibility without binding specificity: limits of AI-based antibody-antigen structure prediction scores
Eva Smorodina, Montader Ali, Klara Kropivšek, Leonardo Salicari, Samo Miklavc, Pietro Sormanni, Ario de Marco, Victor Greiff
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
Conditioning Protein Language Models Using High-Throughput Sequence-Fitness Data Collection
Sonia C. Yuan, Jason Yang, Jinbei Li, Bastian Vogeli, Simon R. Krarup, Emily D. Roberts, Bjarke Erichsen, Vanessa Hurtado Mujica, Kenan Jijakli, Søren Karst, Lei Yang, Alex Toftgaard Nielsen, Tyler Paz Korman, Frances H. Arnold
- Published: 02 Mar 2026, Last Modified: 14 Apr 2026
- GEM 2026
- Readers: Everyone
HallmarkAge: Binarized Hallmark-Aware Transcriptomic Clocks to Discover Aging Mechanisms
Saleem Abdul Fattah Ahmed Al Dajani, Elvira Kinzina, Juhyung Jung, Owen Mulledy, Gonzalo Cardenal-Antolin, Patrick T. Paine, Bohan Zhang, Dmitrii Glubokov, Alexander Tyshkovskiy, John R Williams, Jesse R. Poganik, Vadim N. Gladyshev, Jonathan S. Gootenberg, Omar Abudayyeh
- Published: 02 Mar 2026, Last Modified: 15 Apr 2026
- GEM 2026
- Readers: Everyone
Accelerating Scientific Discovery with Autonomous Goal-evolving Agents
Yuanqi Du, Botao Yu, Tianyu Liu, Tony Shen, Junwu Chen, Jan G. Rittig, Kunyang Sun, Yikun Zhang, Cassandra Masschelein, Yingze Wang, Haorui Wang, Haojun Jia, Chao Zhang, Hongyu Zhao, Martin Ester, Teresa Head-Gordon, Carla P Gomes, Huan Sun, Chenru Duan, Philippe Schwaller et al. (1 additional authors not shown)
Boltz2ESI: Accurate Enzyme Specificity Prediction with Co-folding Foundation Model
Xiwei Cheng, Seonghwan Seo, Jihang Chen, Songlin Jiang, Pengkang Guo, Wengong Jin
- Published: 02 Mar 2026, Last Modified: 14 Apr 2026
- GEM 2026
- Readers: Everyone
Conditionally Site-Independent Neural Evolution of Antibody Sequences
Stephen Zhewen Lu, Aakarsh Vermani, Kohei Sanno, Jiarui Lu, Frederick A Matsen, Milind Jagota, Yun S. Song
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
S2S2Fun: Decoding Protein Function From Latent Structural Representations
Ge Tian, Yunting Hu, Jiaru Li, Jiayi Dou
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
Autoregressive Boltzmann Generators
Danyal Rehman, Charlie B. Tan, Yoshua Bengio, Joey Bose, Alexander Tong
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
mRNA-GPT: End-to-end Generative Design and Optimization of Full-length mRNA
Sizhen Li, Paul Chauvin, Ofek Gross, Michael Bailey, Sven Jager
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
Sequence Design and Phylogenetic Inference with Generative Flow Networks
Qichen Huang, Carlos Michel Mourra-Diaz, Xiaozhen Wen, David Payette
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
ECLIPSE: A Composable Pipeline for Predicting ecDNA Formation, Evolution, and Therapeutic Vulnerabilities in Cancer
Bryan Cheng, Jasper Zhang
- Published: 02 Mar 2026, Last Modified: 06 Apr 2026
- GEM 2026
- Readers: Everyone
The Mechanistic Invariance Test: Genomic Language Models Fail To Learn Positional Regulatory Logic
Bryan Cheng, Jasper Zhang
- Published: 02 Mar 2026, Last Modified: 06 Apr 2026
- GEM 2026
- Readers: Everyone
Generative inverse design of RNA structure and function with gRNAde
Chaitanya K. Joshi, Edoardo Gianni, Samantha L. Y. Kwok, Simon V Mathis, Pietro Lio, Philipp Holliger
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
Information-Theoretic Requirements for Gradient-Based Task Affinity Estimation in Multi-Task Learning
Jasper Zhang, Bryan Cheng
- Published: 02 Mar 2026, Last Modified: 06 Apr 2026
- GEM 2026
- Readers: Everyone
TD3B: Transition-Directed Discrete Diffusion for Allosteric Binder Generation
Hanqun Cao, Aastha Pal, Sophia Tang, Yinuo Zhang, Jingjie Zhang, Pheng-Ann Heng, Pranam Chatterjee
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
PeptiVerse: A Unified Platform for Therapeutic Peptide Property Prediction
Yinuo Zhang, Sophia Tang, Tong Chen, Elizabeth H Mahood, Sophia Vincoff, Pranam Chatterjee
- Published: 02 Mar 2026, Last Modified: 15 Apr 2026
- GEM 2026
- Readers: Everyone
Antigen-specific Antibody Multi-modal Foundation Model for Functional Antibody Design
Zichen Wang, Runze Ma, Xiaoliang Shi, Zhongyue Zhang, Shuangjia Zheng
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
pCoMole: Pareto-Constrained Molecule Editing with Discrete Flows
Tong Chen, Maximilian Holsman, Lin Zhao, Yinuo Zhang, Pranam Chatterjee
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
IN SILICO GENERATIVE DESIGN OF CHEMICALLY MODIFIED RNA SEQUENCES FOR FUNCTIONAL PREDICTION
Mahule Roy, Subhas Roy
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone
A Prospective Experimental Assessment of Structure-Based Drug Design: Are We There Yet?
Maximilian G. Schuh, Joshua Hesse, Konstantin Eckel, Quy Cong Van, Niklas Halbwedl, Frederik Weber, Andres Jäschke, Martin Zacharias, Stephan A. Sieber
- Published: 02 Mar 2026, Last Modified: 13 Apr 2026
- GEM 2026
- Readers: Everyone
AReUReDi: Annealed Rectified Updates for Refining Discrete Flows with Multi-Objective Guidance
Tong Chen, Yinuo Zhang, Sophia Vincoff, Pranam Chatterjee
- Published: 02 Mar 2026, Last Modified: 05 Mar 2026
- GEM 2026
- Readers: Everyone

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Published: 02 Mar 2026, Last Modified: 05 Mar 2026

GEM 2026

Readers: Everyone